Crobn's disease with carcinoma of the colon.

Crohn's disease is not usually regarded as a premalignant state. Recent reviews of the literature1' 2 make scant reference to an association of regional enteritis with carcinoma. However, at the World Congress of Gastro-enterology, I958, Crohn observed that he had seen two cases of carcinoma of the small intestine co-existing with regional enteritis.3 Rare cases of carcinoma arising in patients with pre-existing Crohn's disease have been described in both the small and large intestine. Van Patter7 mentions a case of malignant change occurring in association with regional enteritis of the colon, whilst Warren and Sommers8 reported an adenocarcinoma developing in an area of Crohn's disease in the ascending colon. In addition, Ginzburg5 and Kornfeld6 each describe a case of carcinoma arising in the jejunum in areas affected by regional enteritis. In view of this uncommon -association the following case is reported.